For research use only. Not for therapeutic Use.
Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates[1]. Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates which can be used as reagents for signal transduction research and as modulators of cyclic nucleotide-regulated binding proteins and isoenzymes thereof, and as ligands for affinity chromatography, for antibody production or for diagnostic applications e.g. on chip surfaces[1].
| Catalog Number | I017216 |
| CAS Number | 400775-35-1 |
| Synonyms | 3-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-yne |
| Molecular Formula | C18H30O7 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H30O7/c1-3-5-19-7-9-21-11-13-23-15-17-25-18-16-24-14-12-22-10-8-20-6-4-2/h1-2H,5-18H2 |
| InChIKey | WJGHENNJCGFCLO-UHFFFAOYSA-N |
| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCC#C |
| Reference | [1]. Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates. WO2018041942A1. |
