For research use only. Not for therapeutic Use.
Bisaramil hydrochloride（Cat No.:I004306）is a chemical compound used in research for its potential therapeutic properties. It is a derivative of the peptide bisaramil, which has shown activity in modulating certain biological pathways, including those involved in cancer cell proliferation and inflammation. The hydrochloride salt form, which improves solubility and stability, is used in experimental drug development. Bisaramil hydrochloride has been investigated for its effects on specific receptors or enzymes, and it may have applications in cancer treatment, immunomodulation, or other diseases, although further clinical studies are needed to determine its safety and efficacy.
| Catalog Number | I004306 |
| CAS Number | 96480-44-3 (HCl) |
| Synonyms | Bisaramil; NK-1556; NK 1556; NK1556; RGH-2957; RGH 2957; RGH2957.;(1R,5S,9s)-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]nonan-9-yl 4-chlorobenzoate hydrochloride |
| Molecular Formula | C17H24Cl2N2O2 |
| Purity | ≥95% |
| Target | calcium channel antagonist |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| IUPAC Name | [(1R,5S)-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]nonan-9-yl] 4-chlorobenzoate;hydrochloride |
| InChI | InChI=1S/C17H23ClN2O2.ClH/c1-3-20-10-13-8-19(2)9-14(11-20)16(13)22-17(21)12-4-6-15(18)7-5-12;/h4-7,13-14,16H,3,8-11H2,1-2H3;1H/t13-,14+,16?; |
| InChIKey | WLBQWCHCDDUUCW-DNCNHEBUSA-N |
| SMILES | CCN1C[C@H]2CN(C[C@@H](C1)C2OC(=O)C3=CC=C(C=C3)Cl)C.Cl |
| Reference | 1:Chem Pharm Bull (Tokyo). 1994 Nov;42(11):2365-9. Synthesis and biological activity of the metabolites of syn-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]non-9-yl 4-chlorobenzoate hydrochloride.Yamawaki I,Bukovac SW,Sunami A, PMID: 7859336 </br><span>Abstract:</span> Five metabolites of syn-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]non-9-yl 4-chlorobenzoate hydrochloride (YUTAC) (1) were prepared and examined for Na+ current blocking activity in guinea pig ventricular myocytes. These metabolites showed lower inhibitory activities than the parent compound or were inactive. |
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