For research use only. Not for therapeutic Use.
Bisaramil, also known as NK-1556 and RGH-2957, is a calcium channel antagonist and sodium channel antagonist potentially for the treatment of arrhythmia.
| Catalog Number | I004306 |
| CAS Number | 96480-44-3 (HCl) |
| Synonyms | Bisaramil; NK-1556; NK 1556; NK1556; RGH-2957; RGH 2957; RGH2957.;(1R,5S,9s)-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]nonan-9-yl 4-chlorobenzoate hydrochloride |
| Molecular Formula | C17H24Cl2N2O2 |
| Purity | ≥95% |
| Target | calcium channel antagonist |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| Reference | 1:Chem Pharm Bull (Tokyo). 1994 Nov;42(11):2365-9. Synthesis and biological activity of the metabolites of syn-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]non-9-yl 4-chlorobenzoate hydrochloride.Yamawaki I,Bukovac SW,Sunami A, PMID: 7859336 </br><span>Abstract:</span> Five metabolites of syn-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]non-9-yl 4-chlorobenzoate hydrochloride (YUTAC) (1) were prepared and examined for Na+ current blocking activity in guinea pig ventricular myocytes. These metabolites showed lower inhibitory activities than the parent compound or were inactive. |
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