Bisindolylmaleimide VIII Acetic Acid Salt

• CAT Number: R046091
• CAS Number: 138516-31-1
• Molecular Formula: C26H26N4O4
• Molecular Weight: 458.52
• Purity: ≥95%
• Synonyms: 3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Acetic Acid Salt; ?Ro 31-7549 Acetic Acid Salt; Ro 31-7549/001 Acetic Acid Salt
• Target: PKC
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: acetic acid;3-[1-(3-aminopropyl)indol-3-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
• InChI: InChI=1S/C24H22N4O2.C2H4O2/c1-27-13-17(15-7-2-4-9-19(15)27)21-22(24(30)26-23(21)29)18-14-28(12-6-11-25)20-10-5-3-8-16(18)20;1-2(3)4/h2-5,7-10,13-14H,6,11-12,25H2,1H3,(H,26,29,30);1H3,(H,3,4)
• InChIKey: VEOXVBTXROWDAH-UHFFFAOYSA-N
• SMILES: CC(=O)O.CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCN

Bisindolylmaleimide VIII Acetic Acid Salt(Cat No.:R046091) is a chemical compound used in biochemical and pharmacological research. Its action target involves the inhibition and modulation of protein kinase C (PKC). The mode of action includes reversible binding to the ATP-binding site of PKC, interfering with its activity and downstream signaling pathways. Pharmacologically, Bisindolylmaleimide VIII Acetic Acid Salt is not used directly in medical applications. Instead, it serves as a valuable tool in laboratory settings to study PKC’s involvement in cell signaling, cancer progression, inflammation, and other biological processes.