Bithionol sulfoxide

• CAT Number: I005047
• CAS Number: 844-26-8
• Molecular Formula: C12H6Cl4O3S
• Molecular Weight: 372.05
• Purity: ≥95%
• Target: anticaner agent
• Solubility: Soluble in Dimethyl formamide (> 10 mM)
• Storage: Store at -20°C
• IUPAC Name: 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfinylphenol
• InChI: InChI=1S/C12H6Cl4O3S/c13-5-1-7(15)11(17)9(3-5)20(19)10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
• InChIKey: RPAJWWXZIQJVJF-UHFFFAOYSA-N
• SMILES: C1=C(C=C(C(=C1S(=O)C2=C(C(=CC(=C2)Cl)Cl)O)O)Cl)Cl

Bithionol Sulfoxide（Cat No.:I005047）is a derivative of bithionol, known for its antiparasitic and antimicrobial properties. It is effective against a range of parasitic infections, including those caused by trematodes and cestodes, by disrupting oxidative phosphorylation in the parasites’ mitochondria, leading to energy depletion and death. Additionally, Bithionol Sulfoxide exhibits bacteriostatic and fungistatic activity, making it a valuable agent in treating certain bacterial and fungal infections. Its broad-spectrum efficacy and targeted mechanism of action position it as a key compound in research and veterinary parasitology.

Reference

[1]. Ayyagari VN, et al. Bithionol inhibits ovarian cancer cell growth in vitro – studies on mechanism(s) of action. BMC Cancer. 2014 Feb 4;14:61.

[2]. Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). Dis Aquat Organ. 2010 Sep 17;91(3):257-62.