Bixin

• CAT Number: M007802
• CAS Number: 6983-79-5
• Molecular Formula: C25H30O4
• Molecular Weight: 394.5
• Purity: ≥95%
• Synonyms: 6‐Methyl hydrogen (9Z)‐6,6’‐diapocarotene‐6,6’‐dioate; cis-Bixin
• Target: NF-κB
• Storage: -20°C
• IUPAC Name: (2E,4E,6E,8E,10E,12E,14E,16Z,18E)-20-methoxy-4,8,13,17-tetramethyl-20-oxoicosa-2,4,6,8,10,12,14,16,18-nonaenoic acid
• InChI: InChI=1S/C25H30O4/c1-20(12-8-14-22(3)16-18-24(26)27)10-6-7-11-21(2)13-9-15-23(4)17-19-25(28)29-5/h6-19H,1-5H3,(H,26,27)/b7-6+,12-8+,13-9+,18-16+,19-17+,20-10+,21-11+,22-14+,23-15+
• InChIKey: RAFGELQLHMBRHD-IFNPSABLSA-N
• SMILES: CC(=CC=CC=C(C)C=CC=C(C)C=CC(=O)OC)C=CC=C(C)C=CC(=O)O

Bixin (Cat.No:M007802) is a natural red-orange pigment derived from the seeds of the annatto tree (Bixa orellana). It is commonly used as a food coloring agent, particularly in dairy and bakery products. Bixin is known for its stability under various pH conditions, making it a popular choice in the food industry.

Reference

1: Lobato KB, Paese K, Forgearini JC, Guterres SS, Jablonski A, Rios Ade O. Characterisation and stability evaluation of bixin nanocapsules. Food Chem. 2013 Dec 15;141(4):3906-12. doi: 10.1016/j.foodchem.2013.04.135. Epub 2013 Jun 19. PubMed PMID: 23993564.
2: Dos Santos GC, Mendonça LM, Antonucci GA, Dos Santos AC, Antunes LM, Bianchi Mde L. Protective effect of bixin on cisplatin-induced genotoxicity in PC12 cells. Food Chem Toxicol. 2012 Feb;50(2):335-40. doi: 10.1016/j.fct.2011.10.033. Epub 2011 Oct 14. PubMed PMID: 22019694.
3: Marcolino VA, Zanin GM, Durrant LR, Benassi Mde T, Matioli G. Interaction of curcumin and bixin with β-cyclodextrin: complexation methods, stability, and applications in food. J Agric Food Chem. 2011 Apr 13;59(7):3348-57. doi: 10.1021/jf104223k. Epub 2011 Mar 7. PubMed PMID: 21381747.
4: Piva RM, Johann AC, Costa CK, Miguel OG, Rosa ER, de Azevedo-Alanis LR, Trevilatto PC, Ignacio SA, Bettega PV, Gregio AM. Bixin action in the healing process of rats mouth wounds. Curr Pharm Biotechnol. 2013;14(9):785-91. PubMed PMID: 24372269.
5: Rao MP, Manjunath K, Bhagawati ST, Thippeswamy BS. Bixin loaded solid lipid nanoparticles for enhanced hepatoprotection–preparation, characterisation and in vivo evaluation. Int J Pharm. 2014 Oct 1;473(1-2):485-92. doi: 10.1016/j.ijpharm.2014.07.027. Epub 2014 Jul 24. PubMed PMID: 25066077.
6: Smith TJ, Li XE, Drake MA. Short communication: norbixin and bixin partitioning in Cheddar cheese and whey. J Dairy Sci. 2014;97(6):3321-7. doi: 10.3168/jds.2013-7614. Epub 2014 Apr 3. PubMed PMID: 24704237.
7: Rahmalia W, Fabre JF, Usman T, Mouloungui Z. Aprotic solvents effect on the UV-visible absorption spectra of bixin. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Oct 15;131:455-60. doi: 10.1016/j.saa.2014.03.119. Epub 2014 Apr 13. PubMed PMID: 24840486.