For research use only. Not for therapeutic Use.
BLU-222 is an orally effective and selective CDK2 inhibitor. BLU-222 has antitumor activity[1].
| Catalog Number | I040011 |
| CAS Number | 2888704-84-3 |
| Synonyms | N-[3-(difluoromethoxy)-1H-pyrazol-5-yl]-1-(oxan-4-ylmethyl)pyrazolo[3,4-b]pyrazin-6-amine |
| Molecular Formula | C15H17F2N7O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H17F2N7O2/c16-15(17)26-13-5-11(22-23-13)20-12-7-18-10-6-19-24(14(10)21-12)8-9-1-3-25-4-2-9/h5-7,9,15H,1-4,8H2,(H2,20,21,22,23) |
| InChIKey | IFJSYTKOMJJYNP-UHFFFAOYSA-N |
| SMILES | C1COCCC1CN2C3=NC(=CN=C3C=N2)NC4=CC(=NN4)OC(F)F |
| Reference | [1]. Talbot T, et al. Amplified therapeutic targets in high-grade serous ovarian carcinoma – a review of the literature with quantitative appraisal. Cancer Gene Ther. 2023 Jul;30(7):955-963. |
