BMS 182264

• CAT Number: I004398
• CAS Number: 127749-54-6
• Molecular Formula: C15H19N5
• Molecular Weight: 269.35
• Purity: ≥95%
• Synonyms: BMS 182264; BMS-182264; BMS182264;;N-Cyano-N/’-(4-cyanophenyl)-N/’/’-1,2,2-trimethylpropylguanidine
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term or -20 °C for long term
• IUPAC Name: 1-cyano-3-(4-cyanophenyl)-2-(3,3-dimethylbutan-2-yl)guanidine
• InChI: InChI=1S/C15H19N5/c1-11(15(2,3)4)19-14(18-10-17)20-13-7-5-12(9-16)6-8-13/h5-8,11H,1-4H3,(H2,18,19,20)
• InChIKey: PGYDRGZVXVVZQC-UHFFFAOYSA-N
• SMILES: CC(C(C)(C)C)N=C(NC#N)NC1=CC=C(C=C1)C#N

BMS 182264(CAT: I004398) is a potent and selective non-thiol angiotensin-converting enzyme (ACE) inhibitor designed for its long-acting properties. By targeting ACE, it prevents the conversion of angiotensin I to angiotensin II, a key regulator of blood pressure and vascular tone. This mechanism makes BMS 182264 a valuable compound in cardiovascular research, particularly for studying hypertension, heart failure, and related conditions. Its non-thiol structure minimizes the side effects often associated with thiol-based ACE inhibitors, offering a cleaner pharmacological profile for investigating ACE-dependent pathways and developing advanced therapeutic strategies for managing cardiovascular diseases.