BMS-191095

• CAT Number: I002173
• CAS Number: 166095-21-2
• Molecular Formula: C22H21ClN4O2
• Molecular Weight: 408.88
• Purity: ≥95%
• Target: Potassium Channel
• Solubility: DMSO: ≥ 50 mg/mL
• Storage: -20°C
• IUPAC Name: (3R,4S)-4-[4-chloro-N-(1H-imidazol-2-ylmethyl)anilino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile
• InChI: InChI=1S/C22H21ClN4O2/c1-22(2)21(28)20(17-11-14(12-24)3-8-18(17)29-22)27(13-19-25-9-10-26-19)16-6-4-15(23)5-7-16/h3-11,20-21,28H,13H2,1-2H3,(H,25,26)/t20-,21+/m0/s1
• InChIKey: SMIKIPXIDLITMP-LEWJYISDSA-N
• SMILES: CC1([C@@H]([C@H](C2=C(O1)C=CC(=C2)C#N)N(CC3=NC=CN3)C4=CC=C(C=C4)Cl)O)C

BMS-191095(CAT: I002173) is a potent and selective activator of mitochondrial ATP-sensitive potassium (KATP) channels. By opening these channels, it enhances mitochondrial function, protects against oxidative stress, and reduces apoptosis, making it highly relevant in the cardiovascular research field. BMS-191095 is widely utilized to study ischemia-reperfusion injury, cardioprotection, and mitochondrial bioenergetics. Its specificity and efficacy provide valuable insights into mitochondrial signaling pathways and their therapeutic potential for conditions such as myocardial infarction and neurodegenerative diseases. This compound is a critical tool for advancing research in mitochondrial physiology and pharmacology.