For research use only. Not for therapeutic Use.
BMS-2(Cat No.:I023514) is a tyrosine kinase inhibitor that targets multiple receptors including Met, Flt-3, and VEGFR2. It inhibits the kinase activity of these receptors, thereby interfering with their downstream signaling pathways involved in cell growth, survival, and angiogenesis. By blocking these receptors, BMS-2 may have potential therapeutic applications in conditions where aberrant signaling through these receptors contributes to disease progression.
Catalog Number | I023514 |
CAS Number | 888719-03-7 |
Synonyms | BMS2; BMS-2; BMS 2 |
Molecular Formula | C25H16F2N4O3 |
Purity | 98% |
Target | c-Met/HGFR |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 1-(4-Fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxopyridine-3-carboxamide |
InChI | InChI=1S/C25H16F2N4O3/c26-15-3-6-17(7-4-15)31-13-1-2-19(25(31)33)24(32)30-16-5-8-22(20(27)14-16)34-21-10-12-29-23-18(21)9-11-28-23/h1-14H,(H,28,29)(H,30,32) |
InChIKey | OBSFXHDOLBYWRJ-UHFFFAOYSA-N |
SMILES | O=C(C1=CC=CN(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C5C(NC=C5)=NC=C4)C(F)=C3 |