BMS-433771

• CAT Number: I023524
• CAS Number: 543700-68-1
• Molecular Formula: C21H23N5O2
• Molecular Weight: 377.44
• Purity: ≥95%
• Synonyms: 1-cyclopropyl-3-[[1-(4-hydroxybutyl)benzimidazol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one
• InChI: InChI=1S/C21H23N5O2/c27-12-4-3-11-24-17-6-2-1-5-16(17)23-20(24)14-25-19-13-22-10-9-18(19)26(21(25)28)15-7-8-15/h1-2,5-6,9-10,13,15,27H,3-4,7-8,11-12,14H2
• InChIKey: KSHJXDWYTZJUEI-UHFFFAOYSA-N
• SMILES: C1CC1N2C3=C(C=NC=C3)N(C2=O)CC4=NC5=CC=CC=C5N4CCCCO

BMS-433771（Cat No.:I023524）is an investigational small molecule inhibitor targeting the protein kinase Pyk2 (Proline-rich tyrosine kinase 2). Pyk2 is involved in cellular signaling pathways that regulate cell adhesion, migration, and survival, playing a key role in cancer metastasis and inflammation. By inhibiting Pyk2, BMS-433771 aims to block these signaling pathways, reducing tumor growth and metastatic spread, as well as modulating immune responses. Early preclinical studies suggest it may have potential in treating cancer and inflammatory diseases. Ongoing clinical trials are evaluating its safety, efficacy, and therapeutic applications in various disease settings.