BMS-466442

• CAT Number: I012768
• CAS Number: 1598424-76-0
• Molecular Formula: C31H30N4O5
• Molecular Weight: 538.59
• Purity: ≥95%
• IUPAC Name: methyl (2S)-3-(1-benzylimidazol-4-yl)-2-[(5-methoxy-6-phenylmethoxy-1H-indole-2-carbonyl)amino]propanoate
• InChI: InChI=1S/C31H30N4O5/c1-38-28-14-23-13-26(33-25(23)16-29(28)40-19-22-11-7-4-8-12-22)30(36)34-27(31(37)39-2)15-24-18-35(20-32-24)17-21-9-5-3-6-10-21/h3-14,16,18,20,27,33H,15,17,19H2,1-2H3,(H,34,36)/t27-/m0/s1
• SMILES: COC1=C(C=C2C(=C1)C=C(N2)C(=O)N[C@@H](CC3=CN(C=N3)CC4=CC=CC=C4)C(=O)OC)OCC5=CC=CC=C5

BMS-466442 is a selective asc-1 inhibitor with IC50 values of 37 nM and 20 nM in human asc-1 expressing cells and primary cultures, respectively.
KEYWORDS: BMS-466442 | asc-1 inhibitor | BMS466442 | BMS 466442 | CAS [1598424-76-0] | L-Alanine | L-Serine | L-Cysteine | asc | Inhibitor | Proteins | Schizophrenia | Alanine serine cysteine transporter-1

Reference

JM Brown et al. In vitro Characterization of a small molecule inhibitor of the alanine serine cysteine transporter -1 (SLC7A10). J Neurochem. 2014 Apr;129(2):275-83.