BMS-986124

• CAT Number: I004725
• CAS Number: 1447968-71-9
• Molecular Formula: C16H15BrClNO3S2
• Molecular Weight: 448.77
• Purity: ≥95%
• Synonyms: BMS-986122; BMS 986124; BMS986124.;2-(4-bromo-2-methoxyphenyl)-3-((4-chlorophenyl)sulfonyl)thiazolidine
• Target: μ-Opioid Receptor modulator
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term or -20 °C for long term
• IUPAC Name: 2-(4-bromo-2-methoxyphenyl)-3-(4-chlorophenyl)sulfonyl-1,3-thiazolidine
• InChI: InChI=1S/C17H19N2O5S2/c1-12-3-6-14(7-4-12)26(22,23)18-9-10-25-17(18)13-5-8-16(24-2)15(11-13)19(20)21/h3-8,11,17,20H,9-10H2,1-2H3
• InChIKey: AXAIHSGKCYUSAN-UHFFFAOYSA-N
• SMILES: COC1=C(C=CC(=C1)Br)C2N(CCS2)S(=O)(=O)C3=CC=C(C=C3)Cl

BMS-986124(CAT: I004725) is a selective allosteric modulator of the μ-opioid receptor (MOR), widely utilized in neuropharmacological research. By modulating MOR activity through an allosteric binding site, BMS-986124 enhances or fine-tunes the receptor’s response to endogenous or exogenous opioids, offering insights into opioid receptor signaling and its therapeutic applications. This compound is particularly valuable in studies aimed at improving pain management strategies while minimizing side effects such as tolerance and dependence. With high specificity and efficacy, BMS-986124 serves as a critical tool for advancing the understanding of MOR-mediated pathways and developing novel therapies targeting opioid receptors.