BMS-986278

• CAT Number: I047193
• CAS Number: 2170126-74-4
• Molecular Formula: C22H31N5O5
• Molecular Weight: 445.51
• Purity: ≥95%

BMS-986278 is a potent and orally active antagonist of lysophosphatidic acid receptor 1 (LPA1). BMS-986278 exhibits Kbs of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively, and is widely used in the research of pulmonary fibrotic diseases.

Reference

[1] Cheng PTW, et al. J Med Chem. 2021 Nov 11;64(21):15549-15581.