BN-82685

• CAT Number: I023582
• CAS Number: 477603-18-2
• Molecular Formula: C12H15N3O2S
• Molecular Weight: 265.33
• Purity: ≥95%
• Synonyms: 5-[2-(dimethylamino)ethylamino]-2-methyl-1,3-benzothiazole-4,7-dione
• InChI: InChI=1S/C12H15N3O2S/c1-7-14-10-11(17)8(13-4-5-15(2)3)6-9(16)12(10)18-7/h6,13H,4-5H2,1-3H3
• InChIKey: MTUYOFGUEXWKLC-UHFFFAOYSA-N
• SMILES: CC1=NC2=C(S1)C(=O)C=C(C2=O)NCCN(C)C

BN-82685 is a a quinone-based CDC25 inhibitor with IC50 of 201 nM, 117 nM, 109 nM, 160 nM, 249 nM, for CDC25C, CDC25C-cat, CDC25A, CDC25B2, CDC25B3, respectively. BN-82685 plays an important role in cancer research[1].

Reference

[1]. Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124(6):1449-56.
 [Content Brief]