Boc-Aminooxy-PEG2-C2-amine

For research use only. Not for therapeutic Use.

  • CAT Number: I014705
  • CAS Number: 252378-69-1
  • Molecular Formula: C11H24N2O5
  • Molecular Weight: 264.32
  • Purity: ≥95%
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Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


Catalog Number I014705
CAS Number 252378-69-1
Synonyms

tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]carbamate

Molecular Formula C11H24N2O5
Purity ≥95%
InChI InChI=1S/C11H24N2O5/c1-11(2,3)18-10(14)13-17-9-8-16-7-6-15-5-4-12/h4-9,12H2,1-3H3,(H,13,14)
InChIKey LHNRKSSHYXYKTA-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NOCCOCCOCCN
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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