Boc-Asp(OtBu)-OH

• CAT Number: R019133
• CAS Number: 1676-90-0
• Molecular Formula: C13H23NO6
• Molecular Weight: 289.32
• Purity: ≥95%
• Synonyms: (2S)-4-[(2-methylpropan-2-yl)oxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid
• InChI: InChI=1S/C13H23NO6/c1-12(2,3)19-9(15)7-8(10(16)17)14-11(18)20-13(4,5)6/h8H,7H2,1-6H3,(H,14,18)(H,16,17)/t8-/m0/s1
• InChIKey: PHJDCONJXLIIPW-QMMMGPOBSA-N
• SMILES: CC(C)(C)OC(=O)C[C@@H](C(=O)O)NC(=O)OC(C)(C)C

Boc-Asp(OtBu)-OH（Cat No.:R019133）is a protected form of aspartic acid (Asp) used in peptide synthesis. The N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group, while the carboxyl group at the side chain is protected by a tert-butyl (OtBu) ester. This protection strategy prevents unwanted side reactions during peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The Boc group allows for selective deprotection during synthesis, while the OtBu ester enhances stability. This compound is useful for incorporating aspartic acid into peptides while controlling functional group reactivity.