Boc-Cystamine

• CAT Number: I016139
• CAS Number: 485800-26-8
• Molecular Formula: C₉H₂₀N₂O₂S₂
• Molecular Weight: 252.4
• Purity: ≥95%
• Target: ADC Linker

Boc-Cystamine(CAT: I016139) is a cleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs). ADCs are composed of an antibody linked to a cytotoxic drug through a linker, and Boc-Cystamine serves as a potential linker in this context. The linker is designed to be stable in circulation but can be cleaved under specific conditions within target cells, releasing the cytotoxic payload and thereby enabling targeted and selective delivery of the drug to cancer cells or other disease-related targets.

Reference

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.