Boc-Cys(tBu)-OH

• CAT Number: I043016
• CAS Number: 56976-06-8
• Molecular Formula: C12H23NO4S
• Molecular Weight: 277.38
• Purity: ≥95%
• Synonyms: (2R)-3-tert-butylsulfanyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
• InChI: InChI=1S/C12H23NO4S/c1-11(2,3)17-10(16)13-8(9(14)15)7-18-12(4,5)6/h8H,7H2,1-6H3,(H,13,16)(H,14,15)/t8-/m0/s1
• InChIKey: OGARKMDCQCLMCS-QMMMGPOBSA-N
• SMILES: CC(C)(C)OC(=O)N[C@@H](CSC(C)(C)C)C(=O)O

Boc-Cys(tBu)-OH（Cat No.:I043016）is a protected form of cysteine (Cys), where the N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group, and the thiol group of cysteine is protected by a tert-butyl (tBu) group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), to prevent side reactions that might occur at the thiol group. The Boc group allows for selective deprotection of the amine during peptide elongation, while the tBu protection stabilizes the cysteine residue, which is crucial for the formation of disulfide bonds in peptides.