Boc-D-FMK

• CAT Number: R061596
• CAS Number: 187389-53-3
• Molecular Formula: C11H18FNO5
• Molecular Weight: 263.26
• Purity: ≥95%
• Synonyms: (3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid methyl ester; (S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid methyl ester; BAF; Boc-Asp(OMe)-FMK; Boc-Asp(OMe)-fluoromethylketone; BocD.fmk
• Target: Caspase
• Storage: -20°C
• IUPAC Name: methyl (3S)-5-fluoro-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxopentanoate
• InChI: InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1
• InChIKey: MXOOUCRHWJYCAL-ZETCQYMHSA-N
• SMILES: CC(C)(C)OC(=O)N[C@@H](CC(=O)OC)C(=O)CF

Boc-D-FMK（Cat No.:R061596）is a synthetic, cell-permeable caspase inhibitor widely used in apoptosis research. It is a fluoromethyl ketone (FMK) derivative with a Boc-protected amino acid structure that irreversibly binds to the active sites of caspases, blocking their proteolytic activity. By inhibiting caspase-mediated pathways, Boc-D-FMK helps researchers investigate the mechanisms of programmed cell death and the role of caspases in various diseases, including cancer, neurodegeneration, and inflammation. Its specificity and efficacy make it a valuable tool in studying apoptosis and developing therapeutic strategies targeting caspase activity.