Boc-N-Me-Leu-OH

For research use only. Not for therapeutic Use.

  • CAT Number: I043142
  • CAS Number: 53363-89-6
  • Molecular Formula: C12H23NO4
  • Molecular Weight: 245.32
  • Purity: ≥95%
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Boc-N-Me-Leu-OH(Cat No.:I043142)is a derivative of leucine (Leu) where the N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group, and the amino group of leucine is methylated to form N-methyl leucine (N-Me-Leu). This modification prevents side reactions during peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The Boc protection allows for controlled deprotection during peptide elongation. N-methyl leucine introduces steric and electronic modifications to peptides, which can affect their stability, hydrophobicity, and biological activity. This compound is useful for synthesizing modified peptides with specific properties for research and therapeutic applications.


CAS Number 53363-89-6
Synonyms

(2S)-4-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid

Molecular Formula C12H23NO4
Purity ≥95%
IUPAC Name (2S)-4-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid
InChI InChI=1S/C12H23NO4/c1-8(2)7-9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t9-/m0/s1
InChIKey YXJFAOXATCRIKU-VIFPVBQESA-N
SMILES CC(C)C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C
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