Boc-NH-C4-acid

For research use only. Not for therapeutic Use.

  • CAT Number: I016729
  • CAS Number: 27219-07-4
  • Molecular Formula: C10H19NO4
  • Molecular Weight: 217.26
  • Purity: ≥95%
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Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.


Catalog Number I016729
CAS Number 27219-07-4
Synonyms

5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid

Molecular Formula C10H19NO4
Purity ≥95%
InChI InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-7-5-4-6-8(12)13/h4-7H2,1-3H3,(H,11,14)(H,12,13)
InChIKey GFMRZAMDGJIWRB-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)NCCCCC(=O)O
Reference

[1]. [1].Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.
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