For research use only. Not for therapeutic Use.
Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.
Catalog Number | I016729 |
CAS Number | 27219-07-4 |
Synonyms | 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid |
Molecular Formula | C10H19NO4 |
Purity | ≥95% |
InChI | InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-7-5-4-6-8(12)13/h4-7H2,1-3H3,(H,11,14)(H,12,13) |
InChIKey | GFMRZAMDGJIWRB-UHFFFAOYSA-N |
SMILES | CC(C)(C)OC(=O)NCCCCC(=O)O |
Reference | [1]. [1].Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. |