For research use only. Not for therapeutic Use.
Boc-NH-PEG12-CH2CH2COOH(CAT: I015973) is a significant compound in the field of pharmaceutical and chemical synthesis, particularly in the context of PROTAC (PROteolysis TAgeting Chimeras) development. Serving as a PEG (polyethylene glycol)-based linker, Boc-NH-PEG12-CH2CH2COOH plays a pivotal role in constructing PROTAC molecules. These innovative molecules leverage the ubiquitin-proteasome system to selectively degrade specific target proteins. The compound’s structure, with a Boc-protected amine and a PEG spacer, allows for precise attachment and modulation of the PROTAC’s components.
| Catalog Number | I015973 |
| CAS Number | 1415981-79-1 |
| Molecular Formula | C₃₂H₆₃NO₁₆ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
