Boc-NH-PEG2-C2-NHS ester

• CAT Number: I016641
• CAS Number: 2183440-73-3
• Molecular Formula: C₁₆H₂₆N₂O₈
• Molecular Weight: 374.39
• Purity: ≥95%
• Target: PROTAC Linkers

Boc-NH-PEG2-C2-NHS ester(CAT: I016641) is a compound used in bioconjugation and drug delivery applications. It is a pegylated derivative with a Boc (tert-butyloxycarbonyl) protecting group on the amino group, a PEG2 (polyethylene glycol) linker, and an NHS ester group at the terminus. The NHS ester allows for selective coupling with primary amines, enabling the conjugation of the compound to biomolecules or surfaces. The PEG linker provides increased solubility, flexibility, and stability to the conjugates. Boc-NH-PEG2-C2-NHS ester is commonly used in the synthesis of peptide and protein conjugates for various research and biomedical applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562