Boc-NH-PEG3-CH2COOH

• CAT Number: I017204
• CAS Number: 462100-06-7
• Molecular Formula: C₁₃H₂₅NO₇
• Molecular Weight: 307.34
• Purity: ≥95%
• Target: PROTAC Linkers

Boc-NH-PEG3-CH2COOH(CAT: I017204) is a compound used in bioconjugation and chemical modification strategies. It consists of a Boc (tert-butoxycarbonyl) protecting group, a PEG (polyethylene glycol) chain with three ethylene glycol units, and a carboxylic acid group. The Boc protecting group is commonly used to temporarily mask or protect amine groups during chemical reactions. The PEG chain provides solubility and flexibility to the compound. The carboxylic acid group can be used for conjugation reactions with primary amines or other functional groups. Boc-NH-PEG3-CH2COOH is often used in the synthesis of peptide and protein conjugates, as well as in the development of drug delivery systems and biomaterials.

Reference

[1]. Vollmer S, et al. Design, Synthesis, and Biological Evaluation of MEK PROTACs. J Med Chem. 2020 Jan 9;63(1):157-162.