For research use only. Not for therapeutic Use.
Boc-NH-PEG3-NHS ester(CAT: I016640) is a compound used in bioconjugation and drug delivery applications. It belongs to the class of N-hydroxysuccinimide (NHS) esters and contains a polyethylene glycol (PEG) linker with three ethylene glycol units (PEG3) and a Boc (tert-butoxycarbonyl) protected amino group (NH). The NHS ester group enables the compound to react selectively with primary amines, forming stable amide bonds. Boc-NH-PEG3-NHS ester is commonly utilized for site-specific conjugation of molecules, such as peptides or proteins, to amine-containing biomolecules or surfaces. The PEG linker provides hydrophilicity and flexibility, enhancing the solubility and stability of the conjugates.
Catalog Number | I016640 |
CAS Number | 2250216-93-2 |
Molecular Formula | C₁₈H₃₀N₂O₉ |
Purity | ≥95% |
Target | PROTAC Linkers |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |