Boc-NH-PEG3-propargyl

• CAT Number: I015746
• CAS Number: 1333880-60-6
• Molecular Formula: C₁₄H₂₅NO₅
• Molecular Weight: 287.35
• Purity: ≥95%
• Target: PROTAC Linkers

Boc-NH-PEG3-propargyl (CAT: I015746) is a compound that consists of a polyethylene glycol (PEG) spacer attached to a propargyl group, with a Boc (tert-butoxycarbonyl) protecting group on the amino terminus. It is commonly used as a building block in organic synthesis and drug development. The PEG spacer provides hydrophilicity and flexibility, while the propargyl group offers reactivity for further chemical modifications. The Boc protecting group can be removed under appropriate conditions to expose the free amine for subsequent reactions.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562