Boc-NH-PEG6-CH2CH2COOH

• CAT Number: I016714
• CAS Number: 882847-13-4
• Molecular Formula: C₂₀H₃₉NO₁₀
• Molecular Weight: 453.52
• Purity: ≥95%
• Target: PROTAC

Boc-NH-PEG6-CH2CH2COOH(CAT: I016714) is a chemical compound commonly used in the field of bioconjugation and drug delivery. It is a polyethylene glycol (PEG) derivative with a Boc (tert-butyloxycarbonyl) protecting group at the amino terminus. The PEG spacer, consisting of six ethylene glycol units (PEG6), provides flexibility and water solubility to the molecule. Boc-NH-PEG6-CH2CH2COOH is often used as a linker or spacer molecule to attach drugs, peptides, or other molecules of interest to proteins or nanoparticles. The Boc protecting group can be selectively removed under mild conditions, allowing for further functionalization or conjugation reactions. This compound facilitates the development of drug delivery systems and the synthesis of bioconjugates with improved pharmacokinetic properties and enhanced therapeutic potential.

Reference

[1]. Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.