Boc-Nle-OH

• CAT Number: I043106
• CAS Number: 6404-28-0
• Molecular Formula: C11H21NO4
• Molecular Weight: 231.29
• Purity: ≥95%
• Synonyms: (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
• InChI: InChI=1S/C11H21NO4/c1-5-6-7-8(9(13)14)12-10(15)16-11(2,3)4/h8H,5-7H2,1-4H3,(H,12,15)(H,13,14)/t8-/m0/s1
• InChIKey: ZIOCIQJXEKFHJO-QMMMGPOBSA-N
• SMILES: CCCC[C@@H](C(=O)O)NC(=O)OC(C)(C)C

Boc-Nle-OH（Cat No.:I043106）is a derivative of the amino acid norleucine (Nle), where the N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group. This protection prevents unwanted reactions during peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The carboxyl group remains free for coupling with other amino acids. Boc-Nle-OH is commonly used to incorporate norleucine, a non-natural amino acid, into peptides. Norleucine is structurally similar to leucine, and its use in peptides can influence their stability, hydrophobicity, and biological activity, making this compound valuable in peptide and drug development.