Boc-Pip-butyn

• CAT Number: I043531
• CAS Number: 1346153-07-8
• Molecular Formula: C14H23NO2
• Molecular Weight: 237.34
• Purity: ≥95%
• Synonyms: tert-butyl 4-but-3-ynylpiperidine-1-carboxylate
• InChI: InChI=1S/C14H23NO2/c1-5-6-7-12-8-10-15(11-9-12)13(16)17-14(2,3)4/h1,12H,6-11H2,2-4H3
• InChIKey: QCJJQMHCBVBUPR-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC(CC1)CCC#C

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Reference

[1]. Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61(1):e202110864.
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