Boc-Thr(Me)-OH

• CAT Number: M031963
• CAS Number: 48068-25-3
• Molecular Formula: C10H19NO5
• Molecular Weight: 233.26
• Purity: ≥95%
• Synonyms: (2S,3R)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
• InChI: InChI=1S/C10H19NO5/c1-6(15-5)7(8(12)13)11-9(14)16-10(2,3)4/h6-7H,1-5H3,(H,11,14)(H,12,13)/t6-,7+/m1/s1
• InChIKey: VWSUOKFUIPMDDX-RQJHMYQMSA-N
• SMILES: C[C@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OC

Boc-Thr(Me)-OH（Cat No.:M031963）is a derivative of threonine (Thr) in which the N-terminal amine group is protected by a tert-butoxycarbonyl (Boc) group, and the hydroxyl group of the threonine side chain is methylated to form a methyl ester (Thr(Me)). This modification is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), to prevent unwanted reactions at both the amine and hydroxyl groups. The Boc protection allows for selective deprotection during peptide elongation, while the methyl group on the side chain helps improve peptide stability and solubility, making it useful for bioactive peptide synthesis.