For research use only. Not for therapeutic Use.
BOS-172722 (CAT: I019892) is a chemical compound that acts as an inhibitor of the monopolar spindle 1 (MPS1) checkpoint. The MPS1 checkpoint is a cellular mechanism involved in the regulation of mitosis, specifically the correct attachment and alignment of chromosomes during cell division. By inhibiting MPS1, BOS-172722 disrupts the proper functioning of this checkpoint, leading to abnormalities in chromosome segregation and mitotic progression. This targeted inhibition of MPS1 has potential implications in cancer research and therapy, as dysregulation of the MPS1 checkpoint is often observed in cancer cells.
| Catalog Number | I019892 |
| CAS Number | 1578245-44-9 |
| Molecular Formula | C₂₄H₃₀N₈O |
| Purity | ≥95% |
| Reference | [1]. ARYL SULFONOHYDRAZIDES. WO 2014037750 A1. |
