Box5, a Wnt5a-derived N-butyloxycarbonyl hexapeptide (t-Boc-Met-Asp-Gly-Cys-Glu-Leu), acts as an Wnt5a antagonist, inhibits the basal migration and invasion of Wnt5a-expressing HTB63 melanoma cells, antagonizes the effects of Wnt5a on melanoma cell migration and invasion by directly inhibiting Wnt5a-induced PKC and Ca(2+) signaling.
| Catalog Number | I047194 |
| Purity | ≥95% |
| Reference | [1] Jenei V, et al. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19473-8. |
