For research use only. Not for therapeutic Use.
BPH-715 (Cat.No:I004881) is a new generation of lipophilic bisphosphonates designed as anticancer agents that block protein prenylation also have potent activity against Plasmodium liver stages. BPH-715 proved to be especially potent in cell culture and effectively inh
| Catalog Number | I004881 |
| CAS Number | 1059677-23-4 |
| Synonyms | BPH-715; BPH 715; BPH715; GTPL3196; GTPL 3196; GTPL-3196; Bisphpshonate-715.;hydrogen (2-(3-(decyloxy)pyridin-1-ium-1-yl)-1-phosphonoethyl)phosphonate |
| Molecular Formula | C17H31NO7P2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| IUPAC Name | [2-(3-decoxypyridin-1-ium-1-yl)-1-phosphonoethyl]-hydroxyphosphinate |
| InChI | InChI=1S/C17H31NO7P2/c1-2-3-4-5-6-7-8-9-13-25-16-11-10-12-18(14-16)15-17(26(19,20)21)27(22,23)24/h10-12,14,17H,2-9,13,15H2,1H3,(H3-,19,20,21,22,23,24) |
| InChIKey | QYJHUOZDBUEKQC-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCOC1=C[N+](=CC=C1)CC(P(=O)(O)O)P(=O)(O)[O-] |
| Reference | </br>1: Singh AP, Zhang Y, No JH, Docampo R, Nussenzweig V, Oldfield E. Lipophilic</br> bisphosphonates are potent inhibitors of Plasmodium liver-stage growth.</br> Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93. doi: 10.1128/AA |
