bPiDI

For research use only. Not for therapeutic Use.

  • CAT Number: I040175
  • CAS Number: 525596-64-9
  • Molecular Formula: C22H34I2N2
  • Molecular Weight: 580.33
  • Purity: ≥95%
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bPiDI is a novel selective α6β2 nicotinic receptor antagonist. bPiDI inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs[1].


Catalog Number I040175
CAS Number 525596-64-9
Synonyms

3-methyl-1-[10-(3-methylpyridin-1-ium-1-yl)decyl]pyridin-1-ium;diiodide

Molecular Formula C22H34I2N2
Purity ≥95%
InChI InChI=1S/C22H34N2.2HI/c1-21-13-11-17-23(19-21)15-9-7-5-3-4-6-8-10-16-24-18-12-14-22(2)20-24;;/h11-14,17-20H,3-10,15-16H2,1-2H3;2*1H/q+2;;/p-2
InChIKey GMIGEVLABVAPDI-UHFFFAOYSA-L
SMILES CC1=C[N+](=CC=C1)CCCCCCCCCC[N+]2=CC=CC(=C2)C.[I-].[I-]
Reference

[1]. Thomas E Wooters, et al. bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse. Br J Pharmacol. 2011, 163,2.
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