bpV(phen) (potassium hydrate)

• CAT Number: R064423
• CAS Number: 171202-16-7
• Molecular Formula: C12H8N2O5V • K+(H2O)3
• Molecular Weight: 404.30
• Purity: ≥95%
• Synonyms: Bisperoxovanadium(phen);Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V)
• Target: Metabolic Enzyme/Protease
• Storage: -20°C

bpV(phen) (potassium hydrate)（Cat No.:R064423）is a potent and selective inhibitor of protein tyrosine phosphatases (PTPs), particularly targeting PTEN. By inhibiting PTP activity, it enhances phosphatidylinositol 3-kinase (PI3K) signaling, impacting processes such as cell growth, metabolism, and survival. This compound is widely used in research to investigate the role of PTPs in cancer, insulin signaling, and neurodegenerative diseases. Its ability to modulate key signaling pathways makes bpV(phen) valuable for studying potential therapeutic strategies involving PTP inhibition, especially in oncology and metabolic disorder research.

Reference

1.Lai, J.P.,Dalton, J.T., and Knoell, D.L. Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair. British Journal of Pharmacology 152(8), 1172-1184 (2007).