Br-C3-methyl ester

• CAT Number: I014841
• CAS Number: 4897-84-1
• Molecular Formula: C₅H₉BrO₂
• Molecular Weight: 181.03
• Purity: ≥95%
• Target: PROTAC Linkers
• Storage: Room Temperature
• IUPAC Name: methyl 4-bromobutanoate
• InChI: InChI=1S/C5H9BrO2/c1-8-5(7)3-2-4-6/h2-4H2,1H3
• InChIKey: QAWFLJGZSZIZHO-UHFFFAOYSA-N
• SMILES: COC(=O)CCCBr

Methyl 4-bromobutyrate（Cat No.:I014841） is a compound that can be utilized in the synthesis of cyclopropylmethylcyanide derivatives, which are valuable and highly active compounds. These derivatives serve as significant pharmaceutical intermediates in drug synthesis. They find wide application in the pharmaceutical industry for the development of various drugs. The incorporation of cyclopropylmethylcyanide moieties in drug molecules can enhance their activity and biological properties, making them valuable building blocks in pharmaceutical research and development.

Reference

[1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.