Br-PEG3-C2-Boc

• CAT Number: I016988
• CAS Number: 782475-37-0
• Molecular Formula: C₁₃H₂₅BrO₅
• Molecular Weight: 341.24
• Purity: ≥95%
• Target: PROTAC Linkers

Br-PEG3-C2-Boc (CAT: I016988) is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs (PROteolysis TAgeting Chimeras). This linker contains a bromo functional group that can be used for conjugation to other molecules, allowing for the creation of targeted protein degraders. PROTACs are innovative molecules designed to selectively degrade specific target proteins within cells, offering a promising approach for therapeutic interventions. The use of Br-PEG3-C2-Boc as a linker in PROTAC synthesis facilitates the development of novel therapeutic agents with potential applications in various fields, including drug discovery and targeted protein degradation strategies.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.