For research use only. Not for therapeutic Use.
Br-PEG3-OH (CAT: I016236) serves as a PEG-based PROTAC linker, playing a pivotal role in the synthesis of Proteolysis-Targeting Chimeras (PROTACs). PROTACs are innovative molecules designed to target specific proteins for degradation within cells. Br-PEG3-OH acts as a critical bridging component, connecting the ligand that binds to the target protein with the ligand that recruits an E3 ubiquitin ligase, thus marking the protein for degradation.
| CAS Number | 57641-67-5 |
| Molecular Formula | C₆H₁₃BrO₃ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
