Br-PEG3-OH

For research use only. Not for therapeutic Use.

  • CAT Number: I016236
  • CAS Number: 57641-67-5
  • Molecular Formula: C₆H₁₃BrO₃
  • Molecular Weight: 213.07
  • Purity: ≥95%
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Br-PEG3-OH (CAT: I016236) serves as a PEG-based PROTAC linker, playing a pivotal role in the synthesis of Proteolysis-Targeting Chimeras (PROTACs). PROTACs are innovative molecules designed to target specific proteins for degradation within cells. Br-PEG3-OH acts as a critical bridging component, connecting the ligand that binds to the target protein with the ligand that recruits an E3 ubiquitin ligase, thus marking the protein for degradation.


CAS Number 57641-67-5
Molecular Formula C₆H₁₃BrO₃
Purity ≥95%
Target PROTAC Linkers
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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