For research use only. Not for therapeutic Use.
Br-PEG4-OH(CAT: I016356) serves as a pivotal building block in the realm of PROTAC-based drug development. This PEG-based linker, with its distinctive structure, plays a crucial role in the synthesis of PROTAC molecules. By acting as a bridge between the ligand targeting the protein of interest and the ligand for E3 ubiquitin ligase, Br-PEG4-OH enables the creation of PROTACs designed for targeted protein degradation.
Catalog Number | I016356 |
CAS Number | 85141-94-2 |
Molecular Formula | C₈H₁₇BrO₄ |
Purity | ≥95% |
Target | PROTAC Linkers |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |