For research use only. Not for therapeutic Use.
Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).
Bradykinin (1-6) is a stable metabolite of Bradykinin in rat urine. Bradykinin (BK) is very active in renal function because
it participates in increasing the renal blood flow and in diuresis and natriuresis[1].
| Catalog Number | I020216 |
| CAS Number | 23815-88-5 |
| Synonyms | (2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoic acid |
| Molecular Formula | C30H45N9O8 |
| Purity | ≥95% |
| InChI | InChI=1S/C30H45N9O8/c31-19(9-4-12-34-30(32)33)27(44)39-14-6-11-23(39)28(45)38-13-5-10-22(38)26(43)35-16-24(41)36-20(15-18-7-2-1-3-8-18)25(42)37-21(17-40)29(46)47/h1-3,7-8,19-23,40H,4-6,9-17,31H2,(H,35,43)(H,36,41)(H,37,42)(H,46,47)(H4,32,33,34)/t19-,20-,21-,22-,23-/m0/s1 |
| InChIKey | DXJRNQYAYGIHLF-VUBDRERZSA-N |
| SMILES | C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)O |
| Reference | [1]. Majima M, et al. Diuretic and natriuretic effect of ebelactone B in anesthetized rats by inhibition of a urinary carboxypeptidase Y-like kininase. Jpn J Pharmacol. 1994 May;65(1):79-82. |
