For research use only. Not for therapeutic Use.
BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM[1].
| Catalog Number | I019051 |
| CAS Number | 1660117-38-3 |
| Synonyms | 2,4-dimethyl-6-[6-(oxan-4-yl)-1-[(1S)-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]pyridazin-3-one |
| Molecular Formula | C25H27N5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C25H27N5O2/c1-16-13-21(28-29(3)25(16)31)24-27-22-15-26-20(19-9-11-32-12-10-19)14-23(22)30(24)17(2)18-7-5-4-6-8-18/h4-8,13-15,17,19H,9-12H2,1-3H3/t17-/m0/s1 |
| InChIKey | QNFGQQDKBYVNAS-KRWDZBQOSA-N |
| SMILES | CC1=CC(=NN(C1=O)C)C2=NC3=CN=C(C=C3N2C(C)C4=CC=CC=C4)C5CCOCC5 |
| Reference | [1]. Harald Engelhardt, et al. Pyridinones. WO2015022332A1. |
