BRD4 Inhibitor-20

• CAT Number: I042920
• CAS Number: 2490311-14-1
• Molecular Formula: C18H18N2O4S
• Molecular Weight: 358.41
• Purity: ≥95%
• Synonyms: 2-methoxy-N-(2-oxo-3-propan-2-ylidene-1H-indol-5-yl)benzenesulfonamide
• InChI: InChI=1S/C18H18N2O4S/c1-11(2)17-13-10-12(8-9-14(13)19-18(17)21)20-25(22,23)16-7-5-4-6-15(16)24-3/h4-10,20H,1-3H3,(H,19,21)
• InChIKey: CDERLIUJSXSXFH-UHFFFAOYSA-N
• SMILES: CC(=C1C2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O)C

BRD4 Inhibitor-20（Cat No.:I042920）is a small molecule compound designed to selectively inhibit BRD4, a member of the bromodomain and extraterminal (BET) protein family. BRD4 plays a critical role in regulating gene transcription by binding to acetylated lysine residues on histones and non-histone proteins, influencing cell cycle progression, gene expression, and cancer cell survival. By inhibiting BRD4, BRD4 Inhibitor-20 aims to suppress tumor growth, especially in cancers such as leukemia, lymphoma, and solid tumors. Ongoing research focuses on evaluating its potency, safety, and therapeutic potential in cancer treatment and other diseases.