For research use only. Not for therapeutic Use.
BRD4884 is a potent HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 µM for HDAC1, 2, and 3, respectively[1].
Catalog Number | R066659 |
CAS Number | 1404559-91-6 |
Synonyms | N-[2-amino-5-(4-fluorophenyl)phenyl]oxane-4-carboxamide |
Molecular Formula | C18H19FN2O2 |
Purity | ≥95% |
InChI | InChI=1S/C18H19FN2O2/c19-15-4-1-12(2-5-15)14-3-6-16(20)17(11-14)21-18(22)13-7-9-23-10-8-13/h1-6,11,13H,7-10,20H2,(H,21,22) |
InChIKey | ZFCDNONWGMYBHA-UHFFFAOYSA-N |
SMILES | C1COCCC1C(=O)NC2=C(C=CC(=C2)C3=CC=C(C=C3)F)N |
Reference | [1]. Wagner FF, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chem Sci. 2015 Jan 1;6(1):804-815. |