BRD9539

For research use only. Not for therapeutic Use.

  • CAT Number: I001443
  • CAS Number: 1374601-41-8
  • Molecular Formula: C24H21N3O3
  • Molecular Weight: 399.44
  • Purity: ≥95%
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BRD9539(Cat No.:I001443) is a histone methyltransferase G9a inhibitor with an IC50 of 6.3 μM. BRD9539 also inhibits PRC2 activity and is inactive against SUV39H1, NSD2, and DNMT1. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.


Catalog Number I001443
CAS Number 1374601-41-8
Synonyms

2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid

Molecular Formula C24H21N3O3
Purity ≥95%
Target Histone Methyltransferase
Solubility DMSO ≥ 35 mg/mL
Storage 2-8°C
IUPAC Name 2-benzamido-1-(3-phenylpropyl)benzimidazole-5-carboxylic acid
InChI InChI=1S/C24H21N3O3/c28-22(18-11-5-2-6-12-18)26-24-25-20-16-19(23(29)30)13-14-21(20)27(24)15-7-10-17-8-3-1-4-9-17/h1-6,8-9,11-14,16H,7,10,15H2,(H,29,30)(H,25,26,28)
InChIKey WPXMEOBILYVKBC-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)CCCN2C3=C(C=C(C=C3)C(=O)O)N=C2NC(=O)C4=CC=CC=C4
Reference

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<br>[1]. Yuan Y et al. A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma. ACS Chem Biol. 2012 Jul 20;7(7):1152-7.
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