For research use only. Not for therapeutic Use.
Brefeldin A（Cat No.:I002569）is a lactone antibiotic derived from the fungus Eupenicillium brefeldianum. It is widely used in cell biology research for its ability to inhibit protein transport from the endoplasmic reticulum (ER) to the Golgi apparatus. By disrupting this transport, Brefeldin A induces the redistribution of Golgi proteins back to the ER, effectively blocking secretion and trafficking of proteins. This action is invaluable for studying intracellular protein dynamics, Golgi structure and function, and the mechanisms of vesicular transport. Brefeldin A is a critical tool for elucidating cellular processes and pathways.
| Catalog Number | I002569 |
| CAS Number | 20350-15-6 |
| Synonyms | (1R,2R,3E,7S,11E,13S,15S)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one |
| Molecular Formula | C16H24O4 |
| Purity | ≥95% |
| IUPAC Name | (1R,2R,3E,7S,11E,13S,15S)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one |
| InChI | InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1 |
| InChIKey | KQNZDYYTLMIZCT-KQPMLPITSA-N |
| SMILES | CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O |
