For research use only. Not for therapeutic Use.
Britannilactone(Desacetylinulicin) is a methanol extract of the dried flower of Inula britannica L.
IC50 value:
Target:
A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively [1].
| Catalog Number | I003221 |
| CAS Number | 33620-72-3 |
| Synonyms | (3aS,4S,7aR)-4-hydroxy-5-[(2S)-5-hydroxypentan-2-yl]-6-methyl-3-methylidene-3a,4,7,7a-tetrahydro-1-benzofuran-2-one |
| Molecular Formula | C15H22O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H22O4/c1-8(5-4-6-16)12-9(2)7-11-13(14(12)17)10(3)15(18)19-11/h8,11,13-14,16-17H,3-7H2,1-2H3/t8-,11+,13+,14+/m0/s1 |
| InChIKey | ASZIGQFYGXSPCO-UBVLEBKSSA-N |
| SMILES | CC1=C(C(C2C(C1)OC(=O)C2=C)O)C(C)CCCO |
| Reference | [1]. Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37(5):567-74. |
