BRITE-338733

For research use only. Not for therapeutic Use.

  • CAT Number: I015058
  • CAS Number: 503105-88-2
  • Molecular Formula: C₂₇H₃₅N₃O₂
  • Molecular Weight: 433.59
  • Purity: ≥95%
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BRITE-338733(Cat No.:I015058)is a highly potent inhibitor of RecA, an ATPase enzyme involved in DNA-dependent processes. It exhibits significant inhibitory activity against RecA with an IC50 value of 4.7 µM. By targeting RecA, BRITE-338733 disrupts its DNA-dependent ATPase activity, which plays a crucial role in various DNA repair and recombination pathways. The inhibition of RecA by BRITE-338733 offers potential therapeutic applications in the field of DNA repair modulation and may contribute to the development of novel treatments for DNA-related disorders and diseases.


Catalog Number I015058
CAS Number 503105-88-2
Molecular Formula C₂₇H₃₅N₃O₂
Purity ≥95%
Storage Store at -20°C
IUPAC Name 2-[4-(5-ethylfuran-2-yl)-6-[(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridin-2-yl]-4-methylphenol
InChI InChI=1S/C27H35N3O2/c1-7-20-9-11-24(32-20)18-13-22(21-12-17(2)8-10-23(21)31)29-25(14-18)28-19-15-26(3,4)30-27(5,6)16-19/h8-14,19,30-31H,7,15-16H2,1-6H3,(H,28,29)
InChIKey PKYYVDCUXJXUPN-UHFFFAOYSA-N
SMILES CCC1=CC=C(O1)C2=CC(=NC(=C2)NC3CC(NC(C3)(C)C)(C)C)C4=C(C=CC(=C4)C)O
Reference

[1]. Sexton JZ, et al. Novel Inhibitors of E. coli RecA ATPase Activity. Curr Chem Genomics. 2010;4:34-42. Published 2010 May 26.

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