For research use only. Not for therapeutic Use.
Bromhexine-d3 hydrochloride, a premium pharmaceutical research compound designed for advanced respiratory and mucolytic studies. As a deuterated analog of Bromhexine hydrochloride, it offers enhanced stability and improved pharmacokinetic properties. Bromhexine-d3 hydrochloride is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for respiratory conditions and mucus-related disorders. Trusted by leading laboratories, Bromhexine-d3 hydrochloride is your go-to solution for cutting-edge respiratory research. Unlock new possibilities in respiratory treatment with Bromhexine-d3 hydrochloride, where innovation meets reliability.
| Catalog Number | S000224 |
| Molecular Formula | C14H18D3Br2ClN2 |
| Purity | ≥95% |
| IUPAC Name | 2,4-dibromo-6-[[cyclohexyl(trideuteriomethyl)amino]methyl]aniline;hydrochloride |
| InChI | InChI=1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H/i1D3; |
| InChIKey | UCDKONUHZNTQPY-NIIDSAIPSA-N |
| SMILES | [2H]C([2H])([2H])N(CC1=C(C(=CC(=C1)Br)Br)N)C2CCCCC2.Cl |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Jared M Lucas, et al. The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis. Cancer Discov. 2014 Nov;4(11):1310-25. [3]. Li Wen Shen, et al. TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections. Biochimie. 2017 Nov;142:1-10. [4]. Roberto Maggio, et al. Repurposing the mucolytic cough suppressant and TMPRSS2 protease inhibitor bromhexine for the prevention and management of SARS-CoV-2 infection. Pharmacol Res. 2020 Jul;157:104837. [5]. Santosh Chauhan, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun. 2015 Oct 27;6:8620. |
