Bromo-PEG1-C2-azide

For research use only. Not for therapeutic Use.

  • CAT Number: I015795
  • CAS Number: 1144106-65-9
  • Molecular Formula: C₄H₈BrN₃O
  • Molecular Weight: 194.03
  • Purity: ≥95%
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Bromo-PEG1-C2-azide (Cat.No:I015795) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].<br>PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


Catalog Number I015795
CAS Number 1144106-65-9
Molecular Formula C₄H₈BrN₃O
Purity ≥95%
Target PROTAC Linkers
IUPAC Name 1-azido-2-(2-bromoethoxy)ethane
InChI InChI=1S/C4H8BrN3O/c5-1-3-9-4-2-7-8-6/h1-4H2
InChIKey SBVSTNMRZMYOGF-UHFFFAOYSA-N
SMILES C(COCCBr)N=[N+]=[N-]
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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