For research use only. Not for therapeutic Use.
Bromo-PEG2-C2-acid(CAT: I016473) is a PEG-based PROTAC linker. This linker molecule is specifically designed for use in the synthesis of PROTACs (PROteolysis TArgeting Chimeras), a class of compounds that induce targeted protein degradation by harnessing the cellular ubiquitin-proteasome system. The presence of a bromo group, a PEG chain, and a C2-acid moiety in this compound allows it to facilitate the connection between the target protein-binding ligand and the E3 ligase-binding ligand in a PROTAC molecule.
| Catalog Number | I016473 |
| CAS Number | 1807503-92-9 |
| Molecular Formula | C₇H₁₃BrO₄ |
| Purity | ≥95% |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
